Antenatal Thyroid Screening and Childhood Cognitive Function
نویسندگان
چکیده
From the Centre for Endocrine and Diabetes Sciences, Cardiff School of Medicine (J.H.L., R.R., A.B.P.); the Department of Child Psychology, St. David’s Hospital (S.C., R.P.); and the Department of Medical Biochemistry, University Hospital of Wales (R.J.) — all in Cardiff, United Kingdom; Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London (J.P.B., L.M.G., M.J., N.J.W.); and Azienda Ospedaliera Ospedale Infantile Regina Margherita– Sant’Anna, Turin, Italy (A.M., E.C., V.G., M.P., D.D.). Address reprint requests to Dr. Lazarus at the Centre for Endocrine and Diabetes Sciences, Cardiff University School of Medicine, Heath Park, Cardiff, Wales CF14 4XN, United Kingdom, or at [email protected].
منابع مشابه
Antenatal thyroid screening and childhood cognitive function.
BACKGROUND Children born to women with low thyroid hormone levels have been reported to have decreased cognitive function. METHODS We conducted a randomized trial in which pregnant women at a gestation of 15 weeks 6 days or less provided blood samples for measurement of thyrotropin and free thyroxine (T(4)). Women were assigned to a screening group (in which measurements were obtained immedia...
متن کاملLifetime risks of cardiovascular disease.
1. Lazarus JH, Bestwick JP, Channon S, et al. Antenatal thyroid screening and childhood cognitive function. N Engl J Med 2012; 366:493-501. 2. Vanderpump MP, Lazarus JH, Smyth PP, et al. Iodine status of UK schoolgirls: a cross-sectional survey. Lancet 2011;377: 2007-12. 3. Pearce EN, Lazarus JH, Smyth PP, et al. Perchlorate and thiocyanate exposure and thyroid function in first-trimester pregn...
متن کاملThe second wave of the Controlled Antenatal Thyroid Screening (CATS II) study: the cognitive assessment protocol
BACKGROUND Children whose mothers had low thyroid hormone levels during pregnancy have been reported to have decreased cognitive function. The reported research is part of the follow-on study of the Controlled Antenatal Thyroid Screening Study (CATS I), a randomised controlled trial which investigated the impact of treated vs. untreated low thyroid hormone level in women during pregnancy with t...
متن کاملIncidence of Goiter with Benign and Malignat Thyroid Nodules Following Radiotherapy of Scalp in Childhood
We examined 812 subjects with a history of radiation to the head for the treatment of scalp worm infestation in during childhood. 36% of the subjects had goiters grades IA and II3. Another 134 subjects ( 17%) were found to have thyroid nodularity, 85 of whom bad solitary cold nodules. 43 patients whith either a solitary cold nodule or a multinodular goiter with a priominent cold nodule were ope...
متن کاملThe debate on thyroid screening during pregnancy continues.
The current controversy over recommendations for thyroid screening during pregnancy has its origins in the 1999 publication of an observational study based on thyroid function analysis of stored secondtrimester serum samples. In this study, 62 children of mothers identified with thyroid-stimulating hormone (TSH) levels greater than the 98th percentile were compared with 124 children of euthyroi...
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تاریخ انتشار 2012